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Postdoctoral Researcher (CTpd Danes Feb2021)

  1. Date: 9.2.2021
  2. Location: Champalimaud Centre for the Unknown, Lisboa, Portugal
  3. Employer: Champalimaud Foundation
  4. Job type: Full Time
  5. Position: Postdoctoral Positions
  6. Application start: 10.2.2021             Application ends: 9.3.2021

  7. Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud), a private, non-profit research institution in Lisbon, Portugal, is looking for a highly motivated Postdoctoral Researcher to join our research team.
    The available position (one) will focus on identifying the cellular and molecular mechanisms leading to cancer progression and resistance to cancer therapy, in cancers that arise upon the constitutive activation of the Hedgehog signaling pathway. The position involves using state-of-the-art genetic mouse models in combination with generation and engineering of tumour organoids.
    The successful applicant will be integrated into the Sánchez-Danés research group at Champalimaud Research.

    Call reference: CTpd Danes Feb2021

    Work Plan:
    The Postdoctoral Researcher will participate in developing and running in vivo and in vitro experiments aimed at studying the mechanisms involved in response and resistance to cancer therapy. This position will include a broad and evolving range of tasks, including:
    ~ Mouse genetic lineage tracing in different cancer models
    ~ Clonal analysis
    ~ Generation and engineering of tumour organoids
    ~ Functional experiments in vivo and in vitro
    ~ Transcriptional profiling and analysis
    ~ Dissemination and communication of results

    Offered conditions:
    Competitive remuneration package commensurate with skills, qualifications and experience
    Full immersion into a research excellence ecosystem with highly motivated researchers, supported by state-of-the-art technology and continuous development opportunities.

    Minimum salary in line with MSCA guidelines.
    Maximum allowable duration of the scholarships including the respective renewals
    Maximum contract duration: 36 months (April 2021-expected project end March 2024)

    Expected position starting date: 1.april.2021

    Primary location of work: Champalimaud Center for the Unknown

    Source of financing: This appointment will be funded in the first instance through QuantOCancer project (European Union’s Horizon 2020 research and innovation programme grant agreement No 810653).

    Evaluation Committee members: Adriana Sánchez-Danés, PhD Henrique Veiga-Fernandes, PhD Laura Ward, PhD

    Candidate Profile:
    Minimum qualifications: PhD in Biology, Bioengineering, Biotechnology, Medicine or similar relevant field
    Essential skills:
    ~ Ability to drive and work independently on a research project
    ~ Experimental research experience
    ~ Good capacity for team work, critical thinking and communication skills : Fluency in English
    ~ Willing to collaborate with colleagues from other disciplines, including clinicians
    ~ Ability to conduct research with honesty, accountability, professional courtesy and good stewardship in line with the Singapore Statement on Research Integrity

    Desirable skills that will also be considered:
    Experience in:

    ~ Genetic mouse models and/or organoids;
    ~ Genetic engineering techniques
    ~ Biological imaging techniques (i.e. confocal, light sheet);
    ~ (Quantitative) data analysis and visualization

    Application materials (single document to be uploaded)

    ~ CV and letter of motivation
    ~ The contact information of 3 referees (name, affiliation, email address and relation with the candidate). Note: please choose referees who are able to be contacted as part of the evaluation process.
    ~ Proof of qualifications (certificates) may be required at a later date for formalization of the fellowship/contract agreement.
    Evaluation and selection criteria (respecting article 37 of Decree-Law No. 63/2019, of 16 May)

    Evaluation Method
    Candidates will be screened to determine eligibility based on the minimum qualifications listed in call. The evaluation will consist of 3 stages.
    In the first stage, candidates meeting minimum requirements will be scored according to required application materials (letter of motivation: 50% and CV: 50%) and the ten candidates with the highest scores will be shortlisted.
    In the second stage, the referees of the shortlisted candidates will be contacted 7-10 days following the closure of the call. The recommendation letters will count towards the final evaluation, in which the candidates will be scored on their scientific and curricular backgrounds, to be weighted as follows: Motivation letter: 20%; Curriculum Vitae: 50%; letters of recommendation: 30%.
    In the third stage, the 5-6 candidates that obtain the highest scores will be interviewed (in person, or remotely).
    The top candidate will be selected based on presentation of their previous work and structured questions against candidate profile listed in the call.

    How to apply
    Candidates must complete this application form and submit a single annexed .pdf document containing the application materials stated in call (Described above in section Application materials).

    Notification of results
    All candidates will receive a receipt of acknowledgment within 7 days. The highest scoring candidate will be notified by email or telephone. All other candidates will be notified solely by email of the final outcome of the recruitment process.
    After being notified, candidates will have 10 working days to present a claim for redress by email (careers@research.fchampalimaud.org). If no claim is received by the Champalimaud Foundation, the Evaluation Committee’s decision will become definitive.

    About Us
    Research is at the heart of the Champalimaud Centre for the Unknown, a modern research and clinical facility situated on the waterfront in Lisbon, Portugal. The goal of Champalimaud Research (CR) is to perform world-leading fundamental and translational research. Current research work is focused on the fields of neuroscience, physiology and cancer. Champalimaud Research comprises a team of over 400 scientists from around the world. English is the official language of the Centre. Lisbon’s sunny Atlantic Mediterranean climate, vibrant culture and high quality of life make this a great place to live and work.

    Relevant Institutional Information
    In line with our community guidelines, no candidate may be privileged, favored, prejudiced or deprived of any right or excluded from any duty on the basis of age, sex, gender identity, sexual orientation, race/ethnicity, disability, chronic illness, language, nationality, territory of origin, family status (marital, pregnancy and maternity, having or not having dependents), socioeconomic situation, education, religion, political or ideological beliefs, trade union membership, or on any other grounds which are irrelevant to decision-making.
    HR Excellence in Research

    Legal Notices
    This call may be cancelled at any time on or before the Evaluation Committee’s evaluation of all eligible candidates and the recruitment process shall be concluded on the day of the full execution of the signed agreement between the Champalimaud Foundation and the selected candidate.

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