Filippo del Bene
Date: February 08, 2018. 12:00
Location: CCU Seminar Room
Affiliation: Institut Curie, France.
Our group examines neural circuit formation and function in the visual system using in vivo time-lapse microscopy and novel “optogenetic” approaches to monitor and perturb neuronal activity. The zebrafish preparation is ideal for the in vivo study of the visual system (retina and optic tectum) development and function. First of all, the zebrafish brain is much smaller (< 1mm) than that of mammals, while being equally well differentiated (Fig.1). Importantly, the larval fish brain is transparent. This feature enables optical approaches, such as using genetically encoded fluorescent reporters of axonal transport and synaptic formation.