Researchers create a map that highlights the brain circuits associated with mania
In their latest development, published today (August 24th 2020) in the Journal of Clinical Investigation, the scientists at the Neuropsychiatry Unit, working in an international collaboration with colleagues from Harvard Medical School, used a novel neuroimaging method, called Lesion Network Analysis, to construct a connectivity map of brain lesions associated with mania. More precisely than ever, this map highlights the circuits connecting brain lesions that induce mania.
Image: Diogo Matias
The authors thus confirmed that, while no single brain area is lesioned across all cases of secondary manic episodes, lesions are mostly connected to a specific group of regions in the cortex that regulate mood and emotions.
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