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  1. Losing neurons can sometimes not be that bad


    When we started, the current view was that neuronal death must be always detrimental. And much to our surprise, we found that neuronal death actually counteracts [Alzheimer’s] disease – Dina Coelho


  2. Tumour cells conquer territory from their neighbours using a newly discovered mechanism


    How do tumoural cells replace healthy cells to promote tumour progression? Scientists from the Champalimaud Centre for the Unknown and from the Institut Pasteur (Paris, France), identified a mechanism that responds to cell deformation and can be exploited by tumoral cells to squeeze out and kill their neighbours. This mechanism may promote the early expansion of tumours.


  3. Champalimaud Researcher Receives two million euros grant from the European Research Council to study defensive strategies, from neurons to behaviour


    Marta Moita, Deputy Director of the Champalimaud Research Programme and group leader of the Behavioural Neuroscience lab at the Champalimaud Centre for the Unknown, in Lisbon – Portugal, was awarded a two million euros grant from the European Research Council (ERC) to advance her innovative work on the neural basis of defensive behaviours.


  4. Science Snapshot: Navigating Virtual Worlds


    New video showing how the Sensorimotor Integration lab uses virtual reality to study the brain


  5. The Champalimaud Centre for the Unknown is one of the first Academias Gulbenkian do Conhecimento


    This programme targets children and young people up to 25 years of age, with the goal of creating novel approaches that will equip the participants to successfully navigate our rapidly changing world.


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Latest Publications

  • Drugowitsch J, Mendonça A, Mainen ZF, Pouget A (2019) Learning optimal decisions with confidence Proc Natl Acad Sci U S A 116 (49)
  • Pardo-Vazquez JL, Castiñeiras-de Saa JR, Valente M, Damião I, Costa T, Vicente MI, Mendonça AG, Mainen ZF, Renart A (2019) The mechanistic foundation of Weber's law Nat. Neurosci. 22 (9)
  • Maia, A.; Oliveira, J.; Lajnef, M.; Mallet, L.; Tamouza, R.; Leboye, M.; Oliveira-Maia, A. J. (2019) Oxidative and nitrosative stress markers in obsessive-compulsive disorder: a systematic review and meta-analysis Acta Psychiatr Scand
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  • Rao-Ruiz, Priyanka; Couey, Jonathan J.; Marcelo, Ivo M.; Bouwkamp, Christian G.; Slump, Denise E.; Matos, Mariana R.; van der Loo, Rolinka J.; Martins, Gabriela J.; van den Hout, Mirjam; van IJcken, Wilfred F.; Costa, Rui M.; van den Oever, Michel C.; Kus (2019) Engram-specific transcriptome profiling of contextual memory consolidation Nat Commun